Based at the Moffitt Cancer Center, Florida, Cancer Ecology is a small research group led by David Basanta. We are mathematical modellers who work with biologists and clinicians, trying to understand the ecology of tumors and the evolutionary dynamics of cancer progression and resistance to treatment.

Ziv introducing his model of prostate cancer

Ziv introducing his model of prostate cancer A nice math model that explains clinical data and is validated with a biological model. What's not to like? Ziv Frankenstein a postdoc at the department of Integrated Mathematical Oncology and a member of Sandy Anderson's lab and the CancerEvo group. Together we have produced this model that shows how different microenvironments produce different selection pressures on the prostate cancer and thus yield different types of tumour cells. Bottom line? Gleason score is not the only thing you should look at if you are a urooncologist.

He will be giving an oral presentation tomorrow so if you are attending the AACR meeting on cellular heterogeneity (#aacrtme14) in the tumour microenvironment, do come.

Approximating spatial structure with the Ohtsuki-Nowak transform

I am disgusted but curious about this